China nicotinamide manufacturers introduce the application, specifications of nicotinamide

Nicotinamide Introduction:

INCI Molecular M.W.
Nicotinamide, Pyridine-3-Carboxyamide  C6H6N2O 122.13

Solubility: Freely soluble in water and alcohol, soluble in glycerin

Niacinamide or nicotinamide (NAM) is a form of vitamin B3 found in food and used as a dietary supplement and medication.  As a supplement, it is used by mouth to prevent and treat pellagra(niacin deficiency). While nicotinic acid (niacin) may be used for this purpose, niacinamide has the benefit of not causing skin flushing. As a cream, it is used to treat acne.  It is a water soluble vitamin.

Side effects are minimal. At high doses liver problems may occur. Normal amounts are safe for use during pregnancy. Niacinamide is in the vitamin B family of medications, specifically the vitamin B3 complex. It is an amide of nicotinic acid. Foods that contain niacinamide include yeast, meat, milk, and green vegetables.

Niacinamide was discovered between 1935 and 1937. It is on the World Health Organization’s List of Essential Medicines. Niacinamide is available as a generic medication and over the counter. Commercially, niacinamide is made from either nicotinic acid (niacin) or nicotinonitrile.  In a number of countries grains have niacinamide added to them.

Nicotinamide Application:

It belongs to the Vitamin B, participating in metabolism in the body, can be used to prevent pellagra or other niacin defection disease. It’s used for pharmacy, food additiThis product works as follows:

First, melanin is deep in the skin of melanin cell, but this time, it also inside, was later tentacles is transferred to the surrounding keratin cells, nicotinamide can interfere with the transfer of melanin, make melanin has been melanocyte stay inside not to come out, so will not continue to produce melanin melanin cells, Secondly, melanin will not be seen by the human eye on the skin surface, so as to achieve the whitening effect.

Second, niacinamide prove that has a good effect of saccharification, especially after 2015, the word “the saccharification very in-depth research, many physiological diseases showed that with the saccharification (maillard reaction), material produced by the saccharification is brown, can let the skin looks black, so mash resistance also helps to whitening.ves, feed additives, cosmetic, etc.

In a controlled trial of 20 subjects, repeated intermittent coats of nicotinamide at a low concentration (0.2%) were also effective in reducing skin immunosuppression induced by narrow-spectrum UV radiation that mimics sunlight. 0.2% of the concentration is effective, and we usually use nicotinamide based skin care products concentration is generally above 2%, the best concentration of 4%~5%. So apply nicotinamide extract before applying sunscren.

Nicotinamide Specifications:



Appearance (20oC)

white crystalline powder

Melting point:

128-131 °C

Loss on drying:


Residue on ignition:


Heavy metals:


Readily carbonizable:

no more color than Matching Fluid A



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Company Name: Suzhou Springchem International Co., Ltd.
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Country: China