Creative Biolabs Enhances CAR Design & Construction Services by Exclusive Smarter™ Technology Platform

New York, US, September 24, 2019 Inspired by unrelenting drive and a unique concentrate on chimeric antigen receptor (CAR)-engineered T (CAR-T) cell therapy field, Creative Biolabs have been pursuing to become an eminent biotech company with first-class technology and high-quality services. Based on the exclusive Smarter™ Technology Platform, Creative Biolabs is capable of enhancing the comprehensive CAR Design & Construction Services in a superior way.


The CAR-T therapy has earned a stream of recognition as a potent treatment method against a variety of diseases, especially cancers. Backed up by a skillful team comprised of Ph.D. level scientists, Creative Biolabs has established a comprehensive One-Stop CAR-T Therapy Development System, furthermore, in which CAR Design & Construction Services are improved again with more specificity and innovation.


In general, a CAR can be designed and constructed from different perspectives according to its practical use. At Creative Biolabs, all four generations of CARs are provided. The first-generation CAR consists of the intracellular domain from the CD3 ζ- chain and the primary transmitter of signals from endogenous TCRs. The 2nd-generation CARs are designed to combine the intracellular signaling domains from different costimulatory protein receptors incorporated in the cytoplasmic tail of the CAR to enhance the signaling. The 3rd-generation of CARs combines multiple signaling domains to acquire further enhanced activation signals, proliferation, production of cytokines and effective function. The 4th is developed to shape the tumor environment by the inducible release of transgenic immune modifiers.


In addition to the conventional four generations of CARs, the Smarter™ CAR platform for CAR-T cell development is able to offer novel CARs construction services for the next generation CAR discovery, including but not limited to:


Smarter™ Armored CAR Construction

Smarter™ Marked CAR Construction

Smarter™ Conditional CAR Construction

Smarter™ Safety CAR Construction

Smarter™ Dual CAR Construction

Smarter™ Self-destruct CAR Construction

Smarter™ Switch CAR-T Development

Smarter™ Universal ZipCAR Development

Smarter™ Orthogonal Dual-Switch CAR Construction Service

Smarter™ 7 × 19 CAR Construction Service


At Creative Biolabs, the special CARs are designed and undergo intensive research such as TanCAR, physiological CAR (receptor/ligand-based), universal CAR (biotin/avidin-based), VHH-based CAR, CAR-Macrophage, CAR modified NK cells, CAR-T cell therapy with CRISPR platform, CAR-T Cells With PD-1 Antibody, γδ CAR-T.


More information on CAR-T services and products can be reached at


About Creative Biolabs

As a global company, Creative Biolabs has more than 200 talented and well-trained scientists located in different continents working closely with partners from the entire world to develop and produce medicines of tomorrow. Specifically, the established leading experts in TCR and CAR T&NK cell immune therapy development offer the one-stop custom services that cover the entire new drug development pipeline, and an exclusive line of ready-to-use TCR and CAR T&NK cell construction products, such as virus packaging, purification, expansion and titer determination kits. Furthermore, a unique unparalleled CAR construction and production platform has been built up for all four CAR generations.

Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-619-7922
Address:45-1 Ramsey Road
City: Shirley
State: New York
Country: United States