DelveInsight’s “Peripheral T-Cell Lymphoma (PTCL) – Market Insights, Epidemiology, and Market Forecast-2030″ report delivers an in-depth understanding of the Peripheral T-Cell Lymphoma (PTCL), historical and forecasted epidemiology as well as the Peripheral T-Cell Lymphoma (PTCL) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some of the key facts of the Report:
- The estimates suggest higher incidence of PTCL in the United States with 7,368 cases in 2017.
- Market Size of PTCL in the US was found to be USD 616 Million in 2017.
- Peripheral T Cell Lymphoma accounts for approx. about 10% of all Non-Hodgkin’s Lymphoma (NHL) cases.
- PTCLs typically affect middle aged to elderly patients.
Key benefits of the Report
1. Peripheral T-Cell Lymphoma market report covers a descriptive overview and comprehensive insight of the Peripheral T-Cell Lymphoma epidemiology and Peripheral T-Cell Lymphoma market in the 7 MM (United States, EU5 (Germany, Spain, France, Italy, UK) & Japan.)
2. Peripheral T-Cell Lymphoma market report provides insights on the current and emerging therapies.
3. Peripheral T-Cell Lymphoma market report offers a global historical and forecasted market covering drug outreach in 7MM.
4. Peripheral T-Cell Lymphoma market report provides an edge that will help in developing business strategies by understanding trends shaping and driving the Peripheral T-Cell Lymphoma market.
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“According to DelveInsight, PTCL cases in United States demonstrates that most of the patients at the time of diagnosis are in the later stages (III-IV).”
The peripheral T-cell lymphomas (PTCLs) encompass a heterogeneous group of diseases representing approximately ∼10% to 15% of non-Hodgkin lymphomas. It usually develops from mature-stage white blood cells called T-cells and natural killer (NK) cells.
Most PTCL subtypes are aggressive (fast-growing) lymphomas, including PTCL-NOS, AITL, ALCL, enteropathy-type T-cell lymphoma, and extranodal natural killer (NK) cell/T-cell lymphoma.
The exact cause of Peripheral T-cell Lymphoma is unknown, it can be associated with the exposure to Epstein-Barr virus (EBV) or to the human T-cell leukaemia virus-1 (HTLV-1).
The Peripheral T-cell Lymphoma was classified by WHO in 2008 and updated in 2016.
According to this, the Peripheral T-cell Lymphomas can be broadly classified according to the site of origin of the malignant T cell in the body- Nodal, Extranodal, Cutaneous and Leukemic.
With no standard drug treatments available in clinical practice, the response rate of the cancer to conventional chemotherapies is low, the tolerance is poor, relapse often occurs.
Increasing healthcare expenditure, rise in R&D activities, and awareness among patients about the treatment options will support the market growth for PTCL
“As per DelveInsight’s Analysis, Spain had the lowest incident population of 771 cases in 2017 among EU5 countries.”
Some of the key companies working on Peripheral T-Cell Lymphoma are:
- Solasia Pharma
- Aileron Therapeutics
- HUYA Bioscience
- Eisai
And Many Others.
The launch of the emerging therapies is expected to significantly impact the Peripheral T-Cell Lymphoma treatment scenario in the upcoming years:-
Drugs Covered:
- Darinaparsin
- ALRN 6924
- HBI-8000
- E7777
And Many Others.
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Table of Contents:
1. Key Insights
2. Peripheral T-cell Lymphoma (PTCL) Market Overview at a Glance
2.1. Market Share (%) Distribution of Peripheral T-cell Lymphoma (PTCL) in 2017
2.2. Market Share (%) Distribution of Peripheral T-cell Lymphoma (PTCL) in 2030
3. Disease Background and Overview: Peripheral T-cell Lymphoma (PTCL)
3.1. Introduction
3.2. Classification of Peripheral T-cell Lymphoma
3.2.1. WHO Classification System
3.3. Subtypes of Peripheral T cell lymphoma
3.4. Signs and Symptoms
3.5. Cause of Peripheral T-cell Lymphoma
3.6. Pathophysiology
3.7. Staging
3.8. Diagnosis
4. Epidemiology and Patient Population
4.1. Key Findings
5. G8 Total Incident Population of PTCL
6. Country Wise-Epidemiology of PTCL
6.1. United States
6.1.1. Diagnosed Incident Cases of PTCL in United States
6.1.2. Stage Wise Incidence of PTCL Cases in United States
6.1.3. Type Specific Incidence of PTCL in United States
6.2. EU5
6.3. Germany
6.3.1. Diagnosed Incident Cases of PTCL in Germany
6.3.2. Stage Wise Incidence of PTCL Cases in Germany
6.3.3. Type Specific Incidence of PTCL Cases in Germany
6.4. Italy
6.4.1. Diagnosed Incident Cases of PTCL in Italy
6.4.2. Stage Wise Incidence of PTCL in Italy
6.4.3. Type Specific Incidence of PTCL in Italy
6.5. Spain
6.5.1. Diagnosed Incident Cases of PTCL in Spain
6.5.2. Stage Wise Incidence of PTCL Cases in Spain
6.5.3. Type Specific Incidence of PTCL Cases in Spain
6.6. France
6.6.1. Diagnosed incident cases of PTCL in France
6.6.2. Stage Wise Incidence PTCL Cases in France
6.6.3. Type Specific Incidence of PTCL Cases in France
6.7. United Kingdom
6.7.1. Diagnosed Incident Cases of PTCL in United Kingdom
6.7.2. Stage Wise PTCL Cases in United Kingdom
6.7.3. Type Specific Incidence of PTCL Cases in United Kingdom
6.8. Japan
6.7.1. Assumption and Rationale
6.7.2. Diagnosed Incident Cases of PTCL in Japan
6.7.3. Stage Wise PTCL Cases in Japan
6.7.4. Type Specific Incidence of PTCL Cases in Japan
6.9. China
6.7.1. Assumption and Rationale
6.7.2. Diagnosed Incident Cases of PTCL in China
6.7.3. Stage Wise PTCL Cases in China
6.7.4. Type Specific Incidence of PTCL Cases in China
7. Treatment Practices
7.1. Treatment Goals
7.1.1. Treatment for Newly Diagnosed Patients
7.1.2. Treatment for Patients with Relapsed or Refractory PTCL
7.2. Treatment Options
8. Treatment Algorithm
8.1. United States
8.1.1. Nation Comprehensive Cancer Network (NCCN)
8.2. Europe
8.2.1. ESMO Guidelines
8.2.2. Integrated Management Algorithm
9. Unmet Needs
10. Key Cross Competition: Marketed Drugs
10.1. Beleodaq (Belinostat): Onxeo S.A.
10.1.1. Drug Description
10.1.2. Mechanism of Action
10.1.3. Advantages & Disadvantages
10.1.4. Safety and Efficacy of Beleodaq
10.1.5. Product Profile
10.2. Istodax (Romidepsin): Celgene Corporation
10.2.1. Drug Description
10.2.2. Mechanism of Action
10.2.3. Advantages & Disadvantages
10.2.4. Safety and Efficacy of Istodax
10.2.5. Product Profile
10.3. Folotyn (Pralatrexate): Spectrum Pharmaceuticals
10.3.1. Drug Description
10.3.2. Mechanism of Action
10.3.3. Advantages & Disadvantages
10.3.4. Safety and Efficacy of Folotyn
10.3.5. Product Profile
10.4. Poteligeo (Mogamulizumab): Kyowa Hakko Kirin Co, Ltd.
10.4.1. Drug Description
10.4.2. Mechanism of Action
10.4.3. Advantages & Disadvantages
10.4.4. Safety and Efficacy of Poteligeo
10.4.5. Product Profile
10.5. Adcetris (Brentuximab vedotin): Seattle Genetics
10.5.1. Drug Description
10.5.2. Mechanism of Action
10.5.3. Regulatory Milestones
10.5.4. Advantages & Disadvantages
10.5.5. Safety and Efficacy of Adcetris
10.5.6. Product Profile
To be continued in the report…
11. Emerging Drugs Analysis
11.1. Key cross competition- Emerging Therapies
11.2. Denileukin diftitox: Eisai
11.2.1. Product Description
11.2.2. Other Developmental Activities
11.2.3. Clinical Development
11.2.4. Product Profile
11.3. Darinaparsin: Solasia Pharma
11.3.1. Product Description
11.3.2. Other Developmental Activities
11.3.3. Clinical Development
11.3.4. Product Profile
11.4. IPH4102: Innate Pharmaceuticals
11.4.1. Product Description
11.4.2. Other Developmental Activities
11.4.3. Clinical Development
11.4.4. Product Profile
12 Other Promising Candidates
12.1 Masitinib: AB Science
12.1.1 Product Description
12.1.2 Clinical Development
12.1.3 Safety and Efficacy
12.1.4 Product Profile
12.2 Fenretinide: CerRx
12.2.1 Product Description
12.2.2 Other Developmental Activities
12.2.3 Clinical Development
12.2.4 Safety and Efficacy
12.2.5 Product Profile
12.3 Ruxolitinib: Incyte
12.3.1 Product Description
12.3.2 Other Developmental Activities
12.3.3 Clinical Development
12.3.4 Safety and Efficacy
12.3.5 Product Profile
12.4 Tipifarnib: Kura Oncology
12.4.1 Other Developmental Activities
12.4.2 Clinical Development
12.4.3 Safety and Efficacy
12.4.4 Product Description
12.4.5 Product Profile
12.5 Plitidepsin: PharmaMar
12.5.1 Product Description
12.5.2 Other Developmental Activities
12.5.3 Clinical Development
12.5.4 Product Profile
13 Peripheral T-cell Lymphoma (PTCL): G8 Countries Market Analysis
13.1 Key Findings
13.2 Total Market Size of Peripheral T-cell Lymphoma (PTCL) in G8 Countries
13.3 G8: Market Outlook
14 The United States: Market Outlook
14.1 United States Market Size
14.1.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
14.1.2 Market Size of PTCL by Therapies in US
15 EU-5 Countries: Market Outlook
15.1 Germany
15.1.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
15.1.2 Market Size of PTCL by Therapies in Germany
15.2 France
15.2.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
15.2.2 Market Size of PTCL by Therapies in France
15.3 Italy
15.3.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
15.3.2 Market Size of PTCL by Therapies in Italy
15.4 Spain
15.4.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
15.4.2 Market Size of PTCL by Therapies in Spain
15.5 United Kingdom
15.5.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
15.5.2 Market Size of PTCL by Therapies in UK
16 Japan: Market Outlook
16.1 Japan: Market Size
16.1.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
16.1.2 Market Size of PTCL by Therapies in Japan
17 China: Market Outlook
17.1 China: Market Size
17.1.1 Total Market size of Peripheral T-cell Lymphoma (PTCL)
17.1.2 Market Size of PTCL by Therapies in China
18 Market Drivers
19 Market Barriers
20 Appendix
21 Report Methodology
21.1 Sources Used
22 DelveInsight Capabilities
23 Disclaimer
24 About DelveInsight
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