New York, USA – July 19, 2021 – Stable cell lines, immortal cells that can express the interested proteins stably under controlled level, are widely applied in a variety of studies, which can be utilized for the production of the antigen of therapeutic or experimental antibody, functional study, structure determination (NMR spectroscopy, crystallization, and Cryo-EM), drug discovery, and so on. Using a qualified stable cell line to produce target molecules has obviously increased acceptability and reliability in clinical.
As a professional CRO with extensive experience and sophisticated techniques, Creative Biolabs enables custom cell line construction in a one-stop manner, relieving the customers from complex and time-consuming technical challenges.
Highlights:
* A modified FRT/Flp-In recombinase system is used by technicians at Creative Biolabs to produce human proteins in CHO cells and 293 cells for stable expression.
* With a unique series of high-yield vector systems, the available highest yields in common mammalian protein production host cell lines are achieved, with antibody yielding up to 2.0-5.5 grams/liter, 80-120pg/cell/day in specific media.
* The capabilities also extend to engineered bacterial construction and batch fermentation, such as pCD-Bac, a temperature inducible bacterial expression vector that allows the high-yield protein expression in the host E. coli DH5a.
Hybridoma technology is another powerful tool of Creative Biolabs, which assists the development of target molecules, especially for the long-term production of a large number of monoclonal antibodies (mAbs).
Highlights:
* High specificity, affinity, and accuracy of generated antibodies.
* Diverse species to choose from: mouse, rat, hamster, guinea pig, and gene-inhibited mouse.
* Allow for post-translational modifications.
“Stable cell lines enable the production of antigens that are frequently used for generating mAbs by hybridoma,” said a technician, “usually clients request a bundle.”
Visit the official website to learn more about the techniques: https://www.creative-biolabs.com.
Company Overview
Creative Biolabs has achieved some renown as an expert antibody & protein solution provider in the area of pharmaceutical and academic. With high-end technology platforms, specialized scientists, and extensive knowledge, this CRO has established a systematic service workflow, offering first-level one-stop services for the clients working on their diagnostics and therapeutics-related preclinical studies. With expertise in antibody and protein development and engineering skills, Creative Biolabs can help construct the optimal stable cell lines as support of global clients’ projects.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-830-6441
Country: United States
Website: https://www.creative-biolabs.com