Acurx Pharmaceutical’s Reaches Another Milestone With Russell Microcap Inclusion; Shares Extend August Gains (NASDAQ: ACXP)

Acurx Pharmaceuticals (NASDAQ: ACXP) reached another milestone on Thursday after announcing expected inclusion into the Russell Microcap® Index later this month. The preliminary list of new members was posted on Wednesday and is expected to add substantially to ACXP’s institutional exposure over the next year. 

More than that, it’s a solid reflection of ACXP’s ongoing achievement of its drug development objectives for its pipeline of DNA polymerase IIIC inhibitors. Better still, if its pipeline candidates get approved, they would deliver the first of a new class of antibiotics in over 30 years. 

And progress in reaching that goal is making significant strides, with ACXP continuing its work towards completing the clinical development program for its lead antibiotic candidate ibezapolstat, targeting the treatment of C. difficile Infection. Investors should expect ACXP to announce reaching several key milestone catalysts on that program through 2021 and 2022.

The more excellent news is that the Russell inclusion adds to several positive milestones already reached. Beyond making advancements not seen in decades, ACXP is also among the few companies working to bring meaningful antibiotic treatment candidates to market that target massively underserved gram-positive infections. For patients, ACXP can be a life-saver. For investors, it can be a value driver to portfolios. 

Going After Gram-Positive Infections

ACXP is in the right market at the right time. Gram-positive infections range from MRSA, which accounts for 52% of hospitalized patients, to VRE, a condition that has become highly resistant to the current standard of care treatment Vancomycin. Both can be debilitating. Worse yet, they can sometimes be fatal.

While they can be devastating infections, the good news is that ACXP is taking action to fill a void. They are also getting industry attention, with Health Holland recently providing $500,000 to ACXP in a collaborative venture to evaluate DNA Pol IIIC Inhibitors. 

Further, industry-wide calls from the CDC, NIH, BARDA, and CARB-X to treat these underserved infections are getting louder, resulting in potentially more grant funding in the near term. But it’s not just the industry agencies paying attention; regulators are too.

In fact, ACXP’s Phase2a results to treat C. difficile were so compelling that regulators allowed for early termination of that trial with a pass directly to a Phase2b study. Hence, ACXP is proving that being disruptive brings advantages. Moving toward its Phase 2b and Phase 3 trial, that could be excellent news for ACXP, patients, and investors.

Stay Interested In The Near And Long Term Proposition

Indeed, Acurx’s data is impressive. They delivered excellent topline Phase2a trial results to treat EPI in patients with C. difficile. As noted, the results enticed regulators to allow for early termination of its Phase2a arm and a move directly into its Phase 2b study. That allowance saves time, money, and resources. It also highlights that ACXP took a giant step closer to getting an effective treatment for EPI in patients with C. difficile to market. 

Even better, if its Phase 2b trial confirms prior results, ACXP could find itself advancing into a Phase 3 trial with best-in-class front-line treatment expectations. ACXP expects to do just that, following its Phase 2a study that demonstrated a 100% success rate in meeting primary and secondary trial endpoints. And with the trial relatively short in duration, with most patients treated and evaluated over a 28-day cycle, that news can come soon. Thus, catalysts are in play.

But, as compelling as its C. difficile treatment candidate is, don’t think of ACXP as a one-drug opportunity. Instead, consider too that data shows its scalable platform can potentially expedite the creation of other drugs to treat additional gram-positive infections.

Those markets are substantial and also come with an inherent and urgent medical need.

Disrupting Antibiotics Markets In Need Of New Drugs

Its ACX-375C program is also in play. Like ibezapolstat, it intends to earn front-line and best-in-class effectiveness. Early indicators already show potential to counter numerous multi-drug resistant (MDR) and sensitive gram-positive bacterial pathogens. Indeed, despite its pre-clinical status, data shows promise and a reason to pay attention.

The pre-clinical program is a collaborative effort with WuXi App Tec and is one of the few studies evaluating the DNA Pol IIIC inhibitor to treat multiple infections, including Staphylococcus, Streptococcus, and Enterococcal infections. Interim data support that ACX-375C can be effective against more than only those indications, and ACXP expects its treatment profile to extend to numerous other gram-positive resistant bacterial infections.

In fact, ACX-375C platform scalability could open its potential to treat numerous other infections beyond MRSA, VRE, and those mentioned above, including more common indications such as ear and sinus infections, urinary tract infections, bone/joint infections, and pneumonia. Its $500,000 grant from Health Holland may help expedite the collaborative venture. Still, while this program may take into 2022 to get into a more formal clinical setting, updates would be interim value drivers. 

Hence, watch for headlines on the program.

Back Half Of 2021

Inclusion into the Russell is a value driver that shouldn’t

go unnoticed. The better news is that it adds to the value brought through its other programs. And with the technicals showing ACXP ready to bounce higher after reversing off oversold conditions, the remainder of this year looks attractive from both a company and an investor’s perspective. 

And a move higher is well-deserved. ACXP has posted exceptional Phase 2 results in its C. difficile trial, earned expedited advancement to a Phase 2b study, banked grant money to support its trials, and positioned itself to deliver best-in-class front-line treatments to market. That’s a four-fold of reasons to like the stock today. 

Moreover, if results from its late-stage Phase 2b trial are as good as expected, don’t look to T/A for guidance. The stock will likely ramp considerably higher without the charts, making this recent 12% move higher the launching pad for a more appropriate valuation. 

Undoubtedly, ACXP is a stock that should be in investor’s crosshairs. The better strategy, however, may be to pull the investment trigger sooner rather than later.


Disclaimers: Hawk Point Media Group, LLC. (Hawk Point Media) is responsible for the production and distribution of this content. Hawk Point Media is not operated by a licensed broker, a dealer, or a registered investment adviser. It should be expressly understood that under no circumstances does any information published herein represent a recommendation to buy or sell a security. Our reports/releases are a commercial advertisement and are for general information purposes ONLY. We are engaged in the business of marketing and advertising companies for monetary compensation. Never invest in any stock featured on our site or emails unless you can afford to lose your entire investment. The information made available by Hawk Point Media is not intended to be, nor does it constitute, investment advice or recommendations. The contributors may buy and sell securities before and after any particular article, report and publication. In no event shall Hawk Point Media be liable to any member, guest or third party for any damages of any kind arising out of the use of any content or other material published or made available by Hawk Point Media, including, without limitation, any investment losses, lost profits, lost opportunity, special, incidental, indirect, consequential or punitive damages. Past performance is a poor indicator of future performance. The information in this video, article, and in its related newsletters, is not intended to be, nor does it constitute, investment advice or recommendations. Hawk Point Media strongly urges you conduct a complete and independent investigation of the respective companies and consideration of all pertinent risks. Readers are advised to review SEC periodic reports: Forms 10-Q, 10K, Form 8-K, insider reports, Forms 3, 4, 5 Schedule 13D. For some content, Hawk Point Media, its authors, contributors, or its agents, may be compensated for preparing research, video graphics, and editorial content. As part of that content, readers, subscribers, and website viewers, are expected to read the full disclaimers and financial disclosures statement that can be found by clicking HERE.

The Private Securities Litigation Reform Act of 1995 provides investors a safe harbor in regard to forward-looking statements. Any statements that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, goals, assumptions or future events or performance are not statements of historical fact may be forward looking statements. Forward looking statements are based on expectations, estimates, and projections at the time the statements are made that involve a number of risks and uncertainties which could cause actual results or events to differ materially from those presently anticipated. Forward looking statements in this action may be identified through use of words such as projects, foresee, expects, will, anticipates, estimates, believes, understands, or that by statements indicating certain actions & quote; may, could, or might occur. Understand there is no guarantee past performance will be indicative of future results.Investing in micro-cap and growth securities is highly speculative and carries an extremely high degree of risk. It is possible that an investors investment may be lost or impaired due to the speculative nature of the companies profiled.

Media Contact
Company Name: Hawk Point Media
Contact Person: Ken Lawrence
Email: [email protected]
Phone: 3057806988
City: Miami Beach
State: Florida
Country: United States