Alopecia Areata (AA), an autoimmune skin disorder, in which the hair follicles get damaged by a faulty immune system. This faultiness causes the immune system to attack its own body, thus disrupting hair follicles and new hair formation. Biopsies performed have clearly shown the immune lymphocytes travelling in the hair bulbs of the hair follicle. The condition can lead to extreme hair loss in aggravated stages from the entire body, known as Alopecia universalis or it can lead to overall loss of hair from the scalp area, also called Alopecia Totalis.
DelveInsight’s “Alopecia Areata Market Insights, Epidemiology, and Market Forecast-2030″ report delivers an in-depth understanding of the Alopecia Areata, historical and forecasted epidemiology as well as the Alopecia Areata market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Alopecia Areata Symptoms
- Patchy hair loss
- Inflammation of the hair follicles
- Cadaver hairs
- White spots and lines appear
- Pinpoint dents appear
Some facts of Alopecia Areata Market Report:
- According to the Chantal Bolduc et al., 2018, the prevalence of alopecia areata (AA) in the general population is estimated to be 0.1–0.2%. The lifetime risk of developing alopecia areata is estimated to be 1.7%. All races are affected equally by alopecia areata and no increase in prevalence has been found in a particular ethnic group.
- As per the study conducted by Alexandra C. Villasante Fricke et al. in 2015, the scalp is the most common site of involvement, with or without involvement of other body sites (such as the eyebrows, eyelashes, and beard). Specifically, the most common site was the occipital region, involved in 38.4% of males and 33.4% of females. Upon first presentation, 58% of adult patients had patchy hair loss with less than half the scalp involved. On the other hand, in children, 80–85% had mild-to-moderate hair loss involving less than half the scalp.
- As per the National Organization of Rare Disease, alopecia areata is most common among the children and approximately 2.5 million people are suffering from alopecia areata in the United States.
- As per Herbert Pratt et al. 2017, alopecia areata affects approximately two percent of the general population at some point during their lifetime
- According to the National Alopecia Areata Foundation, approximately 6.8 million people in the United States and 147 million worldwide have or will develop alopecia areata at some point in their lives.
- As per Alexandra C Villasante Fricke et al., 2015, patients with AA experience their first onset of AA by age 40 years in 82.6–88% of patients and by age 20 years in 40.2% of patients. The mean age of onset has been reported as between 25.2 and 36.3 years. In children, the mean age of onset has been reported as between ages 5 and 10 years.
Alopecia Areata Treatment Market
The treatments commonly prescribed to AA patients include Injections, Oral, Topical Treatments and Light therapy.
Alopecia Areata Injections:
Steroid injections are commonly used in the treatment of AA, mainly for bald and patchy areas on the scalp. Steroidal injections are injected on the bare part of the affected area. Although it does not stop the hair fall, but effectively helps in regeneration of hair. The treatment is to be repeated in every one to two months.
Alopecia Areata Oral Treatments:
Cortisone tablets are majorly recommended for severe forms of AA. However, cortisone causes major side effects as well. Immunosuppressants such as methotrexate and cyclosporine are also recommended. They work by creating an obstruction for the immune system, but they cannot be ingested for prolonged periods due to serious side effects such as lymphoma, kidney and liver damages etc.
Alopecia Areata Topical Treatments:
Many types of topical treatments are rubbed on the scalp area and other regions of the body including eyebrows and beard. These involve Minoxidil (Rogaine), Anthralin (Dritho-Scalp), clobetasol (Impoyz), Diphencyprone etc.
Alopecia Areata Light Therapy:
This form of therapy uses a combination of psoralens and Ultra-violet light to treat AA.
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Some of Alopecia Areata Companies are:
- Pfizer
- Suzhou Zelgen Biopharmaceuticals
- Eli Lilly and Company
- Incyte Corporation
- Aclaris Therapeutics
- Legacy Healthcare
- Concert Pharmaceuticals
- LEO Pharma
- Bristol-Myers Squibb
- And Many Others
Alopecia Areata Therapies are:
- PF-06651600
- Jaktinib
- Baricitinib
- ATI-502
- Abatacept
- LH-8
- LEO 124249
- CTP-543
- And Many Others
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Table of Contents:
1. Key Insights
2. Executive Summary of Alopecia Areata
3. Competitive Intelligence Analysis for Alopecia Areata
4. Alopecia Areata: Market Overview at a Glance
4.1. Alopecia Areata Total Market Share (%) Distribution in 2018
4.2. Alopecia Areata Total Market Share (%) Distribution in 2030
5. Alopecia Areata: Disease Background and Overview
6. Patient Journey
7. Alopecia Areata Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Alopecia Areata Treatment
11. Marketed Products
List to be continued in report
12. Emerging Therapies
List to be continued in report
13. Alopecia Areata: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Alopecia Areata
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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